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AFLUON Nasal Spray Astelin (Azelastine)

 

 

Afluon nasal spray, available in bottles of 20 ml. with a metered-dose spray pump.

ACTIVITY

Afluon, a phthalazinone derivative of novel structure, is classified as a potent long acting anti-allergic compound.

INDICATIONS

Afluon: The treatment of symptoms of both seasonal allergic rhinitis and acute exacerbations of perennial allergic rhinitis.

CONTRAINDICATIONS

Afluon: Proven allergy against azelastine hydrochloride.

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PRECAUTIONS

Afluon: None reported.

WARNING

Afluon: Use during pregnancy and lactation: Due to the nasal route of administration and the low dose administered, minimal systemic exposure can be expected. However as with all medicines caution should be exercised with use during pregnancy and lactation. Use in the elderly: There have been no specific studies in the elderly. Effects on ability to drive: None reported.

POSOLOGY

Afluon: - Adults and children over 6 years of age: one application (0,14 ml.) in each nostril twice daily (0,56 mg. of azelastine hydrochloride).
- Elderly: There have been no specific studies in the elderly.

INSTRUCTIONS FOR CORRECT USE AND HANDLING OF AFLUON

1. Remove the protective cap.
2. Before first using, press the pump several times (3-4 times) until an even spray emerges.
3. Spray once into each nostril keeping head upright.
4. Wipe and replace the protective cap.

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INTERACTIONS

Afluon: No specific interactions have been studied.

OVERDOSE

Afluon: The results of animal studies show that toxic doses can produce Central Nervous System symptoms, e.g. excitation, tremor, convulsions. Should these occur in humans, symptomatic and supportive treatment should be instigated. Gastric lavage is recommended if the overdose is recent. With the nasal route of administration overdosage reactions are not anticipated.

ADVERSE EFFECTS

Afluon: In rare cases (0,7%), irritation of the inflamed nasal mucosa may occur, with symptoms such as stinging, itching and sneezing. A substance-specific bitter taste may be experienced after administration (often due to incorrect method of application, namely tilting the head too far backwards during administration) which, in some cases, may lead to nausea. In isolated cases epistaxis may be experienced. If you notice any other adverse reaction not mentioned above, consult your doctor or pharmacist.

PRECAUTIONS FOR STORAGE

Afluon: Do not store below 8°C. Do not refrigerate.

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EXPIRY

Afluon must not be used after the expiry date indicated on the box.

 

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