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Esomeprazole

Brand name:Nexium

Generic name: Esomeprazole Magnesium

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Why is Esomeprazole prescribed?

Esomeprazole relieves heartburn and other symptoms caused by the backflow of stomach acid into the canal to the stomach (the esophagus), a condition known as gastroesophageal reflux disease. Esomeprazole is also prescribed to heal the damage (erosive esophagitis) that reflux disease can cause. Prescribed in combination with the antibiotics Biaxin and Amoxil, Esomeprazole is also used to treat the infection that causes most duodenal ulcers (ulcers occurring just beyond the exit from the stomach). Like its sister drug Prilosec, Nexium works by reducing the production of stomach acid.

Most important fact about Esomeprazole

Esomeprazole comes in delayed-release capsules that should be swallowed whole. Be sure to avoid crushing or chewing the capsules.

How should you take Esomeprazole?

Take Esomeprazole at least one hour before meals. Be careful to swallow it whole. If you have trouble swallowing capsules, you can open the capsule and carefully pour the pellets onto one tablespoon of applesauce. The applesauce should not be hot. Mix in the pellets, then swallow the applesauce immediately, without chewing.

If you miss a dose of Esomeprazole

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

Storage instructions for Esomeprazole

Store at room temperature in a tightly closed container.

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What side effects when taking Esomeprazole may occur?

Side effects with Esomeprazole cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Esomeprazole.

More common side effects when taking Esomeprazole may include:

Abdominal pain, diarrhea, headache.

Rare side effects when taking Esomeprazole may include:

Abnormal sense of smell, acne, allergic reaction, anemia, apathy, back pain, black stools, blood disorders, blood in urine, burping, change in bowel habits, chest pain, chills, confusion, constipation, coughing, cramps, difficulty breathing, difficulty swallowing, dizziness, dry mouth, ear infection, earache, enlarged abdomen, enlarged thyroid gland, eye infection, facial swelling, fast or irregular heartbeat, fatigue, fever, flu-like symptoms, flushing, frequent or increased urination, fungal infections, general feeling of illness, hernia, hiccups, high blood pressure, hives, hot flushes, impotence, inability to sleep, increased appetite, indigestion, itching, leg and body swelling, liver problems, loss of appetite, loss of taste, lymph node problems, menstrual problems, migraine, mouth and throat problems, nausea, nervousness, nosebleed, pain, painful joints and muscles, painful urination, prickly or burning sensation, rash, rectal problems, rigidity, ringing in the ears, runny nose, sensitivity to touch, sinus problems, sleep disorders, sleepiness, sore throat, stomach bleeding, stomach pain, stomach upset, sweating, swelling, taste changes, thirst, tremors, urinary tract infection, vaginitis, vertigo, vision changes, vomiting, weakness, weight changes, worsening of arthritis, worsening of asthma, worsening of depression.

Why should Esomeprazole not be prescribed?

If Esomeprazole gives you an allergic reaction, or you've ever had an allergic reaction to Prilosec, you will not be able to use Esomeprazole.

Special warnings about Esomeprazole

The antibiotics prescribed in conjunction with Esomeprazole for the treatment of ulcers have occasionally been known to cause severe side effects and life-threatening allergic reactions. If you've been prescribed this combination, be sure to check the entries on Amoxil and Biaxin for more information.

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Possible food and drug interactions when taking Esomeprazole

If Esomeprazole is taken with certain other drugs, the effects of either could be increased, decreased, or altered.

It is especially important to check with your doctor before combining Esomeprazole with the following:

Diazepam (Valium)
Digoxin (Lanoxin)
Iron salts (Ferro-Sequels)
Ketoconazole (Nizoral)
Warfarin (Coumadin)

There's no problem, however, with combining antacids and Esomeprazole; no unwanted interaction will result.

Special information if you are pregnant or breastfeeding

The effects of Esomeprazole during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, check with your doctor.

Because Esomeprazole is likely to appear in breast milk and could harm a nursing infant, you'll need to choose between taking Esomeprazole or breastfeeding your baby.

Recommended dosages for Esomeprazole

ADULTS

Gastroesophageal Reflux Disease (GERD)
For relief of symptoms, the usual dosage is one 20-milligram capsule daily for 4 weeks. If symptoms persist, your doctor may prescribe an additional 4 weeks of therapy.

Erosive Esophagitis

To heal damage, the dosage is 20 or 40 milligrams of Esomeprazole once daily for 4 to 8 weeks. If you haven't fully healed after 8 weeks, your doctor may prescribe an additional 4 to 8 weeks of therapy. To maintain healing, the dosage is 20 milligrams once daily.

Duodenal Ulcers

As part of a three-drug treatment to rid the body of ulcer-causing *itH. Pylori *ro bacteria, Esomeprazole is prescribed at a dosage of 40 milligrams once daily for 10 days.

If you have severe liver problems, you should take no more than 20 milligrams of Esomeprazole per day.

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Overdosage with Esomeprazole

Esomeprazole taken in excess can have serious consequences. There have been some reports of Esomeprazole overdoses. If you suspect an overdose of Esomeprazole, seek medical attention immediately.

Symptoms of Esomeprazole overdose may include:

Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating

 

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