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Fexofenadine

Generic name: Fexofenadine hydrochloride

Other brand name: Allegra-D, Allegra, Telfast

 


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Why is Fexofenadine prescribed?

Fexofenadine relieves the itchy, runny nose, sneezing, and itchy, red, watery eyes that come with hay fever. Its effect begins in 1 hour and lasts 12 hours, peaking around the second or third hour. Fexofenadine is one of the new type of antihistamines that rarely cause drowsiness.

In addition, to the antihistamine in Allegra, Allegra-D also contains the nasal decongestant pseudoephedrine.

Most important fact about Fexofenadine

Seldane, an antihistamine related to Fexofenadine, has been implicated in dangerous interactions with the common antibiotic erythromycin, the antifungal medication ketoconazole (Nizoral), and several similar drugs. Fexofenadine poses no such risks. It is also safe for people with liver disease.

How should you take Fexofenadine?

Take Fexofenadine, Allegra and Allegra-D only as prescribed.

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If you miss a dose

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

Storage instructions for Fexofenadine

Store at room temperature. Protect blister packs from moisture.

What side effects may occur with Fexofenadine?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Fexofenadine.

Side effects of Fexofenadine may include:
Colds or flu, drowsiness, fatigue, indigestion, menstrual problems, nausea

Side effects of Allegra-D - Fexofenadine may include:
Abdominal pain, agitation, anxiety, back pain, dizziness, dry mouth, headache, heart palpitations, indigestion, insomnia, nausea, nervousness, respiratory tract infection, throat irritation

Why should Fexofenadine not be prescribed?

If Fexofenadine gives you an allergic reaction, avoid it in the future. Do not give either product to children under 12.

Do not take Fexofenadine if you have glaucoma, urination problems, or severe high blood pressure or heart disease. Also avoid taking Fexofenadine within 2 weeks of using an MAO-inhibitor drug such as Marplan, Nardil, or Parnate.

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Special warnings about Fexofenadine

Use Fexofenadine with caution if you have high blood pressure, diabetes, heart disease, increased pressure in the eyes, prostate problems, or hyperthyroidism. Stop using it and check with your doctor if it causes nervousness, dizziness, or sleeplessness.

Possible food and drug interactions when taking Fexofenadine

Check with your doctor before combining Fexofenadine with erythromycin (E.E.S., Ery-Tab, PCE) or ketoconazole (Nizoral). These drugs may increase Fexofenadine's effects.

Fexofenadine should never be taken within 2 weeks of using an MAO-inhibitor drug such as the antidepressants Marplan, Nardil, and Parnate. Also check with your doctor before combining it with the following:

Mecamylamine (Inversine)
Methyldopa (Aldomet)
Reserpine (Diupress, Hydropres)

You should also avoid Fexofenadine if you have a pacemaker and take digoxin (Lanoxin). And you should not combine it with over-the-counter antihistamines and decongestants.

Special information if you are pregnant or breastfeeding

The effects of Fexofenadine during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether Fexofenadine appears in breast milk. If the drug is essential to your health, your doctor may advise you to stop nursing until your treatment is finished.

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Recommended dosage of Fexofenadine

The usual dosage is 1 capsule (60 milligrams) twice a day. People with kidney problems should take only 1 dose a day.

Overdosage of Fexofenadine

An excessive dose of any medicine can have serious consequences. Seek medical attention whenever an overdose of Fexofenadine is suspected.

Symptoms of Fexofenadine overdose may include:
Dizziness, drowsiness, dry mouth

 

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