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Why is Inderal prescribed ? Inderal, a type of medication known as a beta blocker, is used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), changes in heart rhythm, prevention of migraine headache, hereditary tremors, hypertrophic subaortic stenosis (a condition related to exertional angina), and tumors of the adrenal gland. It is also used to reduce the risk of death from recurring heart attack. When used for the treatment of high blood pressure, Inderal is effective alone or combined with other high blood pressure medications, particularly thiazide-type diuretics. Beta blockers decrease the force and rate of heart contractions, reducing the heart's demand for oxygen and lowering blood pressure. Most important fact about Inderal If you have high blood pressure, you must take Inderal regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Inderal; and you must continue taking it even if you are feeling well. Inderal does not cure high blood pressure; it merely keeps it under control. How should you take Inderal? Inderal works best when taken before meals. Take it exactly as prescribed, even if your symptoms have disappeared. Try not to miss any doses. If Inderal is not taken regularly, your condition may worsen. If you miss a dose of Inderal Take it as soon as you remember. If it is within 8 hours of your next scheduled dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time. Storage instructions for Inderal Store at room temperature in a tightly closed, light-resistant container. Protect from freezing or excessive heat. What side effects when taking Inderal may occur ? Side effects of Inderal cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Inderal. Side effects when taking Inderal may include: Abdominal cramps, colitis, congestive heart failure, constipation, decreased sexual ability, depression, diarrhea, difficulty breathing, disorientation, dry eyes, fever with sore throat, hair loss, hallucinations, headache, light-headedness, low blood pressure, lupus erythematosus (a disease of the connective tissue), nausea, rash, reddish or purplish spots on the skin, short-term memory loss, slow heartbeat, tingling, prickling in hands, tiredness, trouble sleeping, upset stomach, visual changes, vivid dreams, vomiting, weakness, worsening of certain heartbeat irregularities. Why should Inderal not be prescribed ? If you have inadequate blood supply to the circulatory system (cardiogenic shock), certain types of irregular heartbeat, a slow heartbeat, bronchial asthma, or severe congestive heart failure, you should not take Inderal. Special warnings about Inderal If you have a history of congestive heart failure, your doctor will prescribe Inderal cautiously. Inderal should not be stopped suddenly. This can cause increased chest pain and heart attack. Dosage should be gradually reduced. If you suffer from asthma or other bronchial conditions, coronary artery disease, or kidney or liver disease, Inderal should be used with caution. Ask your doctor if you should check your pulse while taking Inderal.Inderal can cause your heartbeat to become too slow. Inderal may mask the symptoms of low blood sugar or alter blood sugar levels. In addition, diabetics who experience a severe drop in blood sugar after taking insulin may suffer a spike in blood pressure if they are also taking Inderal. Notify your doctor or dentist that you are taking Inderal if you have a medical emergency, and before you have surgery or dental treatment. Possible food and drug interactions when taking Inderal If Inderal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Inderal with the following: Alcohol Special information if you are pregnant or breastfeeding The effects of Inderal during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Inderal appears in breast milk and could affect a nursing infant. If Inderal is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Inderal is finished. Recommended dosages for Inderal ADULTS All dosages of Inderal, for any problem, must be tailored to the individual. Your doctor will determine when and how often you should take Inderal. If you are over 65, the doctor will probably start with a relatively low dosage. Remember to take it exactly as directed. Hypertension The usual starting dose of Inderal is 40 milligrams 2 times a day. This dose may be in combination with a diuretic. Dosages are gradually increased to between 120 milligrams and 240 milligrams per day for maintenance. In some cases, a dose of 640 milligrams per day may be needed. Depending on the individual, maximum effect of this drug may not be reached for a few days or even several weeks. Some people may do better taking Inderal 3 times a day. Angina Pectoris The usual daily dosage is 80 milligrams to 320 milligrams, divided into 2, 3, or 4 smaller doses. When your treatment is being discontinued, your doctor will reduce the dosage gradually over a period of several weeks. Irregular Heartbeat The usual dose is 10 milligrams to 30 milligrams 3 or 4 times a day, before meals and at bedtime. Heart Attack The usual daily dosage is 180 milligrams to 240 milligrams divided into smaller doses. The usual maximum dose is 240 milligrams, although your doctor may increase the dose when treating heart attack with angina or high blood pressure. Migraine The usual starting dosage is 80 milligrams per day divided into smaller doses. Dosages can be increased gradually to between 160 milligrams and 240 milligrams per day. If this dose does not relieve your symptoms in 4 to 6 weeks, your doctor will slowly take you off Inderal. Tremors The usual starting dose is 40 milligrams, 2 times per day. Symptoms will usually be relieved with a dose of 120 milligrams per day; however, on occasion, dosages of 240 milligrams to 320 milligrams per day may be necessary. Hypertrophic Subaortic Stenosis The usual dose is 20 milligrams to 40 milligrams, 3 to 4 times a day, before meals and at bedtime. Before Adrenal Gland Surgery The usual dose is 60 milligrams a day divided into smaller doses for 3 days before surgery in combination with an alpha-blocker drug. Inderal may also be taken by people with inoperable tumors in doses of 30 milligrams a day, divided into smaller doses. CHILDREN Inderal will be carefully individualized for use in children and is used only for high blood pressure. Doses in children are calculated by body weight, and range from 2 milligrams to 4 milligrams per 2.2 pounds daily, divided into 2 equal doses. The maximum dose is 16 milligrams per 2.2 pounds per day. If treatment is stopped, Inderal must be gradually reduced over a 7- to 14-day period. Inderal is also available in a sustained-release formulation,
called Inderal (ER), for once-a-day dosing. Overdosage with Inderal No specific information on Inderal overdosage is available; However, overdose symptoms with other beta blockers include: Extremely slow heartbeat Irregular heartbeat Low blood pressure Severe congestive heart failure Seizures Wheezing Any medication taken in excess can have serious consequences. If you suspect an overdose of Inderal , seek medical attention immediately.
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