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Brand name: Lyrica, Pregabalin

Generic name: Pregabalin

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What is Pregabalin?

Pregabalin affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. The exact way that it works is unknown. Pregabalin is used with other drugs in the treatment of some types of seizures. Pregabalin is also used for the management of postherpetic neuralgia (nerve pain caused by the herpes virus or shingles) and for diabetic peripheral neuropathy (pain from damaged nerves that happen with diabetes).

What is the most important information I should know about Pregabalin?

If you are taking Pregabalin for seizures, do not stop taking Pregabalin even if you feel better. It is important to continue taking Pregabalin to prevent seizures from recurring. Do not stop taking Pregabalin without talking to your doctor. Stopping suddenly may result in insomnia, nausea, headache, or diarrhea. Pregabalin may cause problems with your vision including blurry vision. Contact your doctor if you experience any changes in vision. Talk to your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, excessive tiredness or fever. Use caution when driving, operating machinery, or performing other hazardous activities. Pregabalin may cause dizziness, sleepiness or blurred vision. If you experience any of these symptoms avoid these activities.

What should I discuss with my doctor before taking Pregabalin?

Before taking Pregabalin, tell your doctor if you have any other medical conditions including:

How should I take Pregabalin ?

Take Pregabalin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose of Pregabalin with a full glass of water.
Pregabalin can be taken with or without food.

Do not stop taking Pregabalin without talking to your doctor. Suddenly stopping Pregabalin may cause side effects.

Store Pregabalin tablets and capsules at room temperature away from moisture and heat.

Dosage of Pregabalin

The maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Dosing should begin at 50 mg three times a day (150 mg/day) and may be increased to 300 mg/day within 1 week based on efficacy and tolerability. Because Pregabalin is eliminated primarily by renal excretion, the dose should be adjusted for patients with reduced renal function

What happens if I miss a dose of Pregabalin ?

Take the missed dose of Pregabalin as soon as you remember. However, if several hours have passed and it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of Pregabalin to catch up.

What happens if I overdose on Pregabalin ?

Seek emergency medical treatment if an overdose is suspected.
Symptoms of a Pregabalin overdose include double vision, drowsiness, slurred speech, diarrhea, poor coordination, and difficulty breathing.

What should I avoid while taking Pregabalin ?

Use caution when driving, operating machinery, or performing other hazardous activities. Lyrica may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Pregabalin will cause drowsiness and fatigue. Avoid alcohol, sleeping pills, antihistamines, sedatives, and tranquilizers that may also make you drowsy except under the supervision of your doctor.

What are the possible side effects of Pregabalin?

If you experience any of the following serious side effects, stop taking Lyrica and seek medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
Other, side effects may be more likely to occur. Talk to your doctor if you experience
dizziness, poor coordination, or drowsiness;
blurred or double vision;
weight gain and swelling of the hands and feet;
unexplained muscle problems, such as muscle pain, soreness, or weakness;
dry mouth; or
tremor.
Pregabalin caused skin sores in animals. Although skin sores were not seen in studies in people, if you have diabetes, you should pay extra attention to your skin while taking Pregabalin and tell your doctor of any sores or skin problems.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Pregabalin?

Tell your doctor about all the medicines you take including prescription or non- prescription medicines, vitamins or herbal supplements. Pregabalin and other medicines may affect each other.

Especially tell your doctor if you take:

rosiglitazone (Avandia) or pioglitazone (Actos) for diabetes. You may have a higher chance of weight gain or swelling if these medicines are taken with Lyrica.
any narcotic pain medicine (such as oxycodone), tranquilizers or medicines for anxiety (such as lorazepam). You may have a higher chance for dizziness and sleepiness if these medicines are taken with Pregabalin.
any medicines that make you sleepy Know all the medicines you take. Keep a list of them with you to show your doctor and pharmacist each time you get a new medicine.
Drugs other than those listed here may also interact with Pregabalin or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

 

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